Xandar (odds of dying: DECEASED)
Okay, so Xandar is a planet and not a character, but it is home to some beloved characters. The Nova Corps, led by Nova Prime (Glenn Close) is headquartered there. Denarian Dey (John C. Reilly) and his family are there, as are the Broker (Christopher Fairbank) and his eyebrows.
We saw the Nova Corps take possession of the purple Power Stone at the end of Guardians of the Galaxy, In the trailer, Thanos already has it in his gauntlet as he drops the Space Stone (from the Tesseract) in, so we know the Power Stone is the first one he acquires. Xandar is probably his first stop and there is no way he takes the Power Stone gently.
The first time we see him in Infinity War, Thanos will finish what Ronan couldn’t and use the Power Stone to destroy Xandar and everyone on it before using that same stone to attack Thor and the people of Asgard.
Thanos (odds of dying: Xandar and all other victims will be AVENGED)
Thanos is the most powerful villain The Avengers have ever faced. They will suffer heavy losses that will forever change the MCU as we know it.
But they will win.
The Avengers and Guardians will not be whole, but they will ultimately be victorious. That is what they do and Thanos will find out that hard way. He’s too powerful to simply be knocked out and housed in some intergalactic prison. He will have to be put down once and for all and The Avengers and Guardians will eventually get the job done.